20 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs) Elevation ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Injury • AST/ALT elevation ... AnnKumfer #Liver #Enzymes ... Transaminitis #diagnosis #differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... - Differential ... Algorithm ALP: - Enzymes ... Other causes of elevation ... #Differential #
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... to 10-20-fold elevation ... Elevated Liver enzymes ... to 10-20-fold elevation ... hepatitis #comparison #differential
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
/or suspicious clinical ... the magnitude of enzyme ... elevation and clinical ... Hepatology #Liver #Enzymes ... #Differential #
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... a cytoplasmic enzyme ... red blood cell enzymes ... Idiosyncratic LDH Elevation ... Dehydrogenase #Elevated #differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Bilirubin - +/- elevation ... or amyloid: • Elevation ... Source of Liver Enzyme ... Elevation: • ... chemistry #diagnosis #differential
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
sulfate → Sulfatase enzyme ... pathophysiology #clinical ... #photo #differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Bilirubin - +/- elevation ... Source of Liver Enzyme ... Elevation: • ... injury #hepatitis #differential
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... cardiomyopathy - Elevation ... of muscle enzyme