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causes hematology lactate rheumatology syndrome acidosis bronchiectasis cardiology classification dehydrogenase dermatology dm2 elevated erythematosus false hba1c hepatic hepatology hgba1c hiv
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
== Decreased RBC ... RBC turnover • Acute ... End-stage renal disease ... #Diagnosis #DM2 ... #Differential
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... ALT and AST - Elevations ... —100-fold with acute ... chronic liver disease ... #Diagnosis #Testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity is the diagnostic ... hallmark for the disease ... Mild-to-moderate elevation ... WBC count and differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... myocarditis, rheumatic fever ... Idiosyncratic LDH Elevation ... #diagnosis #Laboratory
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - APLS • Acute ... Fragility: • Decreased ... mountain spotted fever
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... presentations and disease ... - assess other laboratory ... muscle use • Decreased ... #Differential #
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Headache (45%) • Fever ... - Liver enzyme elevation ... T-cell count can decrease ... ART to slow HIV disease ... Syndrome #HIV #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Diagnosis Framework ... Muscle swelling - Fever ... ULN • AST/ALT Elevation ... vasoconstriction → decreased ... of underlying disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... ) and laboratory ... Classification: • Acute ... permanent alopecia Differential ... to: Arthritis, Fever
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
run-down or tired • Fevers ... Connective tissue diseases ... Bronchoscopy Laboratory ... Bronchiectasis #pulmonary #differential ... #diagnosis
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