26 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False Elevation ... • Asplenia Laboratory ... HbA1c #HgbA1c #Laboratory ... #Diagnosis #DM2 ... #Differential
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Regions - Frequent Differential ... Diagnoses Medical ... Jaundice (and/or elevation ... Returning #Traveler #differential ... #diagnosis #tropical
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity is the diagnostic ... Mild-to-moderate decrease ... Mild-to-moderate elevation ... WBC count and differential
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Diagnosis Ferritin ... Decreased hepcidin ... Infection -16% ... Infection - 46% ... extreme ferritin elevation
Infectious Diarrhea - Laboratory Testing

Clostridium difficile
Salmonella enterica, Shigella spp, Campylobacter spp 
Salmonella enterica serovars Typhi and
Infectious Diarrhea ... - Laboratory Testing ... Paratyphi (enteric fever ... #Diarrhea #diagnosis ... #differential #
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... without platelet decrease ... inclusions - If infection ... bartonella (oroya fever
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Delivery (DO2) • Decreased ... Pain / Exercise, Fever ... Localized soft-tissue infection ... Syndrome, where decreased
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Headache (45%) • Fever ... - Liver enzyme elevation ... T-cell count can decrease ... Viral hepatitis Diagnosis ... Syndrome #HIV #diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Hyperferritinemia, decreased ... fraction < 20% Differential ... Diaqnoses: • ... Infectious: Mycoplasma
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Diagnosis Framework ... • Toxins • Infection ... myocarditis, rheumatic fever ... Idiosyncratic LDH Elevation ... #diagnosis #Laboratory