24 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
• Asplenia Laboratory ... Reduction == Increase ... #Increase #Decrease ... #Diagnosis #DM2 ... #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity is the diagnostic ... Mild-to-moderate decrease ... Mild-to-moderate elevation ... WBC count and differential
Tuberculous Pleural Effusions - Tests and Biomarkers
Age + fever + red blood cells + ADA -
Biomarkers Age + fever ... IFN-y + NAAT - Increase ... #Tuberculosis #Laboratory ... #Testing #diagnosis
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
Diagnosis Ferritin ... Increased hepcidin ... Decreased hepcidin ... extreme ferritin elevation ... #Diagnosis #Causes
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
Laboratory Evaluation ... ; decreased radioactive ... sedimentation rate normal; decreased ... #hyperthyroid #differential ... #diagnosis #endocrinology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... without platelet decrease ... bartonella (oroya fever ... #Diagnosis #Algorithm
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... inflammation: Increased ... Hyperferritinemia, decreased ... fraction < 20% Differential ... Diaqnoses: •
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Delivery (DO2) • Decreased ... Compartment Syndrome • Increased ... Pain / Exercise, Fever ... Syndrome, where decreased
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Emergencies - Differential ... Diagnosis Framework ... death Neutropenic Fever ... , hypotension, increased ... • Vomiting, decreased
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... - assess other laboratory ... Circulatory System • Increased ... muscle use • Decreased ... #Differential #