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diagnosis hepatology lfts algorithm causes comparison hepatitis infections infectiousdiseases transaminitis travel aflp ascites chemistry dehydrogenase disease elevated enzymes heat heatstroke
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Regions - Frequent Differential ... amebic abscess of liver ... Jaundice (and/or elevation ... of liver enzymes ... Returning #Traveler #differential
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... - If both are normal ... or amyloid: • Elevation ... Enzyme Elevation ... chemistry #diagnosis #differential
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
to 10-20-fold elevation ... Hepatic imaging: Normal ... • Histology: Normal-mild ... to 10-20-fold elevation ... hepatitis #comparison #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Bilirubin - +/- elevation ... function may be abnormal ... Enzyme Elevation ... injury #hepatitis #differential
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... initial response to abnormal ... magnitude of enzyme elevation ... *Abnormal USS may ... #Enzymes #Differential
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - ... Differential Diagnosis ... resolution falling to normal ... Brucellosis • Liver ... #Patterns #Differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... RBCs, muscle, liver ... upon damage • Normal ... myocarditis, rheumatic fever ... Idiosyncratic LDH Elevation
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Heat Stroke - Differential ... Muscles, Kidneys, Liver ... - Core temp normal ... acidosis - CPK elevation ... heat #illness #differential
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites Normal ... Liver disease ... - Acute fatty liver ... Mediterranean fever ... Causes #diagnosis #differential
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