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diagnosis hepatology differential lfts causes injury transaminitis management abnormal acute alcoholic arld chemistry chronic dehydrogenase dili druginduced elevated enzymes fatigue
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... HSV • Toxic: Alcohol ... Medication, Pregnancy, Alcoholic ... Hepatitis, TPN ... Causes #Acute #algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • NAFLD • Alcohol ... Ducts • PSC • Alcoholic ... hepatitis • Drugs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Bilirubin - +/- elevation ... ALT Ratios: • Alcoholic ... Enzyme Elevation
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... ALT Ratios: • Alcoholic ... Enzyme Elevation ... differential #diagnosis #algorithm
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Induced Hepatitis ... Differential #Diagnosis #Algorithm
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... • Infections: Hepatitis ... Drugs (MDMA), Alcohol ... Diagnosis #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... can be bridge to Liver ... #Hepatitis #Management ... #Algorithm #treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... HEV, EBV, CMV), Alcohol-related ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... Injury #Diagnosis #Algorithm
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... magnitude of enzyme elevation ... aminotransferase; ARLD, alcohol-related ... dehydrogenase; NAFLD, non-alcoholic ... LFTs #Abnormal #Algorithm
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