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diagnosis differential hepatology hepatitis lfts interpretation transaminitis aflp aih alkaline alp autoimmune bilirubin causes chemistry clinical comparison conjugated creactiveprotein crp
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... • Normal • ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... Differential Diagnosis Algorithm ... Other causes of elevation ... consult ALP elevation ... Phosphatase #ALP #Elevation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... - If both are normal ... or amyloid: • Elevation ... of ALP • Near normal ... Enzyme Elevation
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... function may be abnormal ... Enzyme Elevation ... differential #diagnosis #algorithm
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... to 10-20-fold elevation ... Hepatic imaging: Normal ... • Histology: Normal-mild ... to 10-20-fold elevation
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... magnitude of enzyme elevation ... #Algorithm #Hepatology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Differential Diagnosis Algorithm ... Definition: T.bili elevation ... MRCP, ERCP, liver ... Differential #Diagnosis #Algorithm
C-REACTIVE PROTEIN Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
synthesized by the liver ... or minor elevation ... mg/L: Moderate elevation ... 10.0 mg/L: Marked elevation ... 50.0 mg/L: Severe elevation
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... hepatocellular pattern of liver ... upper limit of normal ... (rare) - IgG Elevation
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