11 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... Elevation and Reduction ... HbA1c == False Elevation ... Transfusions #False #Elevation ... Diagnosis #DM2 #Differential
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
Algorithm for the ... the most likely cause ... recovery also causes ... an elevation in ... #Workup #AAFP
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... and Causes Increased ... Hemolysis #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... Intestine - Other causes ... of elevation: ... consult ALP elevation ... Phosphatase #ALP #Elevation
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
- Differential ... saturation to differentiate ... Sideroblastic anemia ... extreme ferritin elevation ... Hyperferritinemia #Differential
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Hyperbilirubinemia - Differential ... Diagnosis Algorithm ... Definition: T.bili elevation ... non-ICU vs ICU causes ... #Diagnosis #Algorithm
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
Guidelines for Crises ... include: • ST elevation ... calcium. ❽ Treat anaemia ... persistent ST elevation ... Diagnosis #Management #Workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... immune hemolytic anemia ... Mild-to-moderate elevation ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... Levels Acute CK Elevation ... Subacute to Chronic Causes ... Electrolytes: hypo- phos, kalemia ... #Elevated #CK #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... Acidosis - Differential ... Elevation Type ... 30mmHg) - Severe anemia ... Lactic #Acidosis #Elevation