22 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Algorithm for evaluation of elevated serum alkaline phosphatase.

#Algorithm #elevated #alkaline #phosphatase #AlkPhos #Elevation #Diagnosis #workup
Algorithm for evaluation ... of elevated serum ... #Algorithm #elevated ... phosphatase #AlkPhos #Elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... Differential Diagnosis Algorithm ... Other causes of elevation ... consult ALP elevation ... Phosphatase #ALP #Elevation
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Mild jaundice, Elevated ... to 10-20-fold elevation ... Syndrome (Hemolysis, Elevated ... to 10-20-fold elevation
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... specificity to elevated ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... specificity to elevated ... Bilirubin - +/- elevation ... Enzyme Elevation ... differential #diagnosis #algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... Viral, Ischemia, AIH ... kwburak #LFTs #Elevated ... Transaminitis #Algorithm
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... IgG typically elevated ... If suspected, AIH ... (rare) - IgG Elevation
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Differential Diagnosis Algorithm ... Definition: T.bili elevation ... MRCP, ERCP, liver ... Differential #Diagnosis #Algorithm
C-REACTIVE PROTEIN
Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
synthesized by the liver ... Normal or minor elevation ... mg/L: Moderate elevation ... 10.0 mg/L: Marked elevation ... 50.0 mg/L: Severe elevation