23 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... Transaminase >> Alkaline ... Cholestatic Pattern - Alkaline ... #FunctionTest # ... LFTs #Elevation
Algorithm for evaluation of elevated serum alkaline phosphatase.

#Algorithm #elevated #alkaline #phosphatase #AlkPhos #Elevation #Diagnosis #workup
Algorithm for evaluation ... of elevated serum ... alkaline phosphatase ... #Algorithm #elevated ... #AlkPhos #Elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
(ALP) Elevation ... Differential Diagnosis Algorithm ... Other causes of elevation ... consult ALP elevation ... Phosphatase #ALP #Elevation
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Injury • AST/ALT elevation ... + ULN ALT) / (alkaline ... phosphatase + ULN alkaline
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... synthesized in: liver ... intracranial pressure - Elevated ... eliminated • Elevation ... phosphate &/or • Elevation
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... Tests - AST, ALT, Alkaline ... In liver, 80% of ... Alkaline phosphatase ... hepatocyte - Elevation
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Mild jaundice, Elevated ... to 10-20-fold elevation ... Syndrome (Hemolysis, Elevated ... to 10-20-fold elevation
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... LFTs #Abnormal #Algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... specificity to elevated ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... specificity to elevated ... Bilirubin - +/- elevation ... Enzyme Elevation ... differential #diagnosis #algorithm