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diagnosis hepatology lfts causes lactate transaminitis abnormal acidosis aflp aih alkaline alp autoimmune bilirubin chemistry chronic classification comparison conjugated dehydrogenase
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Phosphatase (ALP) Elevation ... - Differential ... Other causes of elevation ... consult ALP elevation ... Phosphatase #ALP #Elevation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation ... chemistry #diagnosis #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Bilirubin - +/- elevation ... Enzyme Elevation ... #differential #
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... to 10-20-fold elevation ... to 10-20-fold elevation ... hepatology #obstetrics #hepatitis ... #comparison #differential
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Hyperbilirubinemia - Differential ... Diagnosis Algorithm ... Definition: T.bili elevation ... MRCP, ERCP, liver ... #Diagnosis #Algorithm
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Regions - Frequent Differential ... - HIV, herpes, hepatitis ... B, hepatitis C ... Jaundice (and/or elevation ... Returning #Traveler #differential
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... disease to acute liver ... hepatocellular pattern of liver ... (rare) - IgG Elevation ... #Autoimmune #Hepatitis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue - Differential ... Diagnosis Algorithm ... Renal Failure • Liver ... Epstein-Barr Virus • Hepatitis ... • Drug Abuse (e.g
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... RBCs, muscle, liver ... • Ischemic hepatitis ... Idiosyncratic LDH Elevation ... Dehydrogenase #Elevated #differential
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