11 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... #Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Bilirubin - +/- elevation ... Enzyme Elevation ... differential #diagnosis #algorithm
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... /or suspicious clinical ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... LFTs #Abnormal #Algorithm
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
weeks • Typical clinical ... to 10-20-fold elevation ... post-partum • Typical clinical ... to 10-20-fold elevation ... of Pregnancy (AFLP
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... synthesized in: liver ... is critical for ... eliminated • Elevation ... phosphate &/or • Elevation
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis Clinical ... Highly variable clinical ... disease to acute liver ... hepatocellular pattern of liver ... (rare) - IgG Elevation
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Get an LP and imaging ... Returning Traveler’ algorithm ... duplex or CTA • Liver ... Liver biopsy • ... node biopsy • Clinical
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
if they have no clinical ... anemia for age, elevation ... of ALT, platelets ... purposes of this algorithm ... those >day 10 with clinical
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... no significant elevation ... disease and ILD • Liver ... elevated levels of ALT ... Liver biopsies show