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diagnosis hepatology differential lfts injury management aflp causes obstetrics pregnancy transaminitis abnormal acute aih alcohol arld autoimmune comparison disease enzymes
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
to 10-20-fold elevation ... , no necrosis HELLP ... to 10-20-fold elevation ... hepatology #obstetrics #hepatitis ... diagnosis #icp #HELLP
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... NAFLD, Autoimmune hepatitis ... biliary obstruction, HELLP ... Sepsis, Viral Hepatitis ... Causes #Acute #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... • Pregnancy: HELLP ... Bilirubin - +/- elevation ... Enzyme Elevation ... differential #diagnosis #algorithm
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... • Infections: Hepatitis ... NAFLD, Autoimmune, HELLP ... Diagnosis #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Pregnancy - AFLP, HELLP ... • Alcoholic hepatitis ... Differential #Diagnosis #Algorithm
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... Diagnosis: Viral Hepatitis ... Preeclampsia, HELLP ... Maternal Support - Critical
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... Clinical Presentation ... disease to acute liver ... hepatocellular pattern of liver ... (rare) - IgG Elevation
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... evaluation of the clinical ... /or suspicious clinical ... magnitude of enzyme elevation ... LFTs #Abnormal #Algorithm
Alcohol-related liver disease algorithm. In patients in whom alcohol is suspected to be the main injurious
Alcohol-related liver ... disease algorithm ... fibrosis is the critical ... #LiverDisease #algorithm ... #ARLD #Hepatitis
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