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diagnosis hepatology saag albumin algorithm causes gradient pathophysiology serum abdominal aflp analysis chronic clinical elevation fatty fluid histoplasmosis humoral hypertension
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... SinaiBmoreIMRes #Liver ... #FunctionTest #
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... SAAG ≥ 1.1: - Ascitic ... syndrome, Massive liver ... metastases - Ascitic ... gradient #hepatology #differential
Deciphering the SAAG - Serum to Ascites Albumin Gradient Ascites is either made in the liver sinusoid
SAAG - Serum to Ascites ... Albumin Gradient Ascites ... either made in the liver ... or not by the liver ... Interpretation #Differential
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Differential ... disease • Acute liver ... amzn.to/2LmUODZ #Ascites ... #Differential #
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... Chylous <1% #Ascites ... #Differential #
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... Liver disease ... - Acute fatty liver ... - Bile ascites ... Causes #diagnosis #differential
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... portal HTN: • Ascites ... sarcoidosis) • Liver ... metastasis • Fatty liver
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... develops (DIC, ascites ... infiltration) Differential
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Serum Ascites Albumin ... Gradient (SAAG) - Differential ... - Massive liver ... - Acute fatty liver ... Albumin #Gradient #Differential
Common Malignancies That Cause Ascites The most common malignancies causing ascites are ovarian cancer, pancreatic cancer, gastric
carcinomatosis or liver ... peritoneal seeding or liver ... peritoneum or liver ... malnutrition or liver ... #Differential #
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