9 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Hepatopathy • Acute ... Viral Hepatitis ... (>1000): • DILI ... ) • Non-hepatic
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... specific for the liver ... abnormality vs bone Bili ... SinaiBmoreIMRes #Liver ... #FunctionTest #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ... dechallenge • Acute ... presentation: Hepatic ... #Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • Hepatic vein: ... • Iatrogenic: DILI ... Tests of synthetic function
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... , Acute biliary ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... replaced by non-hepatic ... Chronic viral hepatitis ... Unconjugated Bili
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
synthetic function ... • Cirrhosis/acute ... hepatitis • Infiltrative ... sarcoidosis) • Liver ... metastasis • Fatty liver
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... Maddrey Discriminant Function ... Treatment: - Acute ... HCV, DILI, HCC,
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Diseases • Septic ... Screening Tests for Acute ... IgM) levels • Hepatitis ... profile, including liver ... function tests