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diagnosis hepatology injury lfts transaminitis causes elevation gastroenterology management abdominal abscess acute alkaline alp ascites bleed chemistry chronic drug druginduced
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... abnormality vs bone Bili ... SinaiBmoreIMRes #Liver ... #FunctionTest #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... disease, Hepatic ... presentation: Hepatic ... Injury #Diagnosis #Algorithm
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... or symptoms of liver ... Drug #induced #Liver ... Idiosyncratic #differential ... gastroenterology #algorithm
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - Differential ... (>1000): • DILI ... ) • Non-hepatic ... #Tests #LFTs #Differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... • Iatrogenic: DILI
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... #Injury #Differential ... Causes #Acute #algorithm
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites - Differential ... Diagnosis Algorithm ... Hypertension - Hepatic ... disease • Acute liver ... #Diagnosis #Algorithm
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... replaced by non-hepatic ... Unconjugated Bili ... > 90% of Total Bili ... chemistry #diagnosis #differential
Upper GI Bleed - Management Algorithm Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR Initial Stabilization Concern for
Bleed - Management Algorithm ... Stabilization Concern for Liver ... GI Bleed: • Peptic ... GAVE (idiopathic, liver ... UGIB #GIBleed #Differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... elevation DDX of Hepatic
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