14 results
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... imaging: Normal ... Syndrome (Hemolysis, Elevated ... to 10-20-fold elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... Intestine - Other causes ... DDX of Hepatic
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Injury: • Hepatic ... specificity to elevated ... Enzyme Elevation
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Laboratory Findings in Hepatic ... / Liver Failure ... - Elevated conjugated ... ALT and AST - Elevations ... #LiverFailure #Hepatic
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... with elevated Mean ... Differential Diagnosis Algorithm ... Deficiency - Abnormal ... #Causes #Hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... <45% and SF is normal ... If other causes ... hemochromatosis; HIC, hepatic ... hemochromatosis #algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... Bilirubin - +/- elevation ... replaced by non-hepatic ... or amyloid: • Elevation ... Enzyme Elevation
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... disease US — Normal ... Differential #Diagnosis #Algorithm ... #Causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
fibrinogen • Elevated ... DIC • Severe Liver ... Treat primary cause ... 100mg/dL) - Heparin ... Coagulation #diagnosis #causes
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... or slightly elevated ... early on but elevated ... or higher • Liver ... malignancies, Hepatic