12 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
to 10-20-fold elevation ... , no necrosis HELLP ... enzymes, and Low ... to 10-20-fold elevation ... diagnosis #icp #HELLP
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Injury • AST/ALT elevation ... more specific for hepatic ... #Enzymes #LFTs
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... ALP: - Enzymes ... disturbance (obstructed liver ... Highest • Bone • Liver ... DDX of Hepatic
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... • Pregnancy: HELLP ... Enzyme Elevation
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute Liver ... biliary obstruction, HELLP ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... Causes #Acute #algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Pregnancy - AFLP, HELLP ... Differential #Diagnosis #Algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Bilirubin - +/- elevation ... replaced by non-hepatic ... or amyloid: • Elevation ... Enzyme Elevation
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... the magnitude of enzyme ... elevation and clinical ... LFTs #Abnormal #Algorithm ... #Enzymes #Differential
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... enzymes, or family ... enzymes to rule ... hemochromatosis; HIC, hepatic ... hemochromatosis #algorithm