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diagnosis hepatology differential lfts algorithm injury interpretation abnormal arthritis bleeding bruising cardiogenic cardiology causes checklist chemistry chf disease elevated elevation
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... SinaiBmoreIMRes #Liver ... #FunctionTest # ... LFTs #Elevation #Transaminitis
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Pulmonary Function ... #Pulmonary #FunctionTests
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Hepatopathy • Acute ... (Drug-induced liver ... #Function #Tests ... Diagnosis #hepatology #transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... Elevated #Abnormal #Transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Hepatocellular - Check Acute ... Mixed - Check Acute ... Imperative to Identify Acute ... Cirrhosis: > 1 • Acute ... differential #Hepatology #transaminitis
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
manifestations of acute ... liver failure ... abnormalities Liver ... Loss of metabolic function ... #liver #failure
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #Patterns #Liver ... hepatology #LFTs #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Vascular Causes of Acute ... Hepatocellular Acute ... Cholestatic Acute ... Tests of synthetic function
Etiology of Acute Liver Failure – bolded entities are most likely to cause AST/ALT in the
Etiology of Acute ... Liver Failure – ... 1000s #Diagnosis #Acute ... #LiverFailure #Transaminitis
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
hepatic synthetic function ... • Cirrhosis/acute ... sarcoidosis) • Liver ... metastasis • Fatty liver
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