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diagnosis hepatology differential lfts algorithm chemistry elevation failure hepatitis interpretation manifestations patterns rvalue signs symptoms tests
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... Hepatocellular injury ... 2: Cholestatic injury ... #FunctionTest # ... LFTs #Elevation #Transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Hepatopathy • Acute ... injury) • Ischemic ... #Function #Tests ... Diagnosis #hepatology #transaminitis
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
liver failure ... abnormalities Liver ... Loss of metabolic function ... Subclinical myocardial injury ... lung injury,
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... > 20x normal - Acute ... #Patterns #Liver ... #LFTs #transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Mixed - Check Acute ... injury < 26 weeks ... hepatocellular injury ... muscle injury: ... differential #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Liver Injury: ... Liver Injury: ... Liver Injury: ... Tests of synthetic function
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