7 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... specific for the liver ... SinaiBmoreIMRes #Liver ... #FunctionTest # ... LFTs #Elevation #Transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... or AST > ALP): ... kwburak #LFTs #Elevated ... #Abnormal #Transaminitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... specificity to elevated ... > ALP: Typical ... Cholestasis • ALP ... differential #Hepatology #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... (Drug-induced liver ... LouLectures #Liver ... #Function #Tests ... Diagnosis #hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... specificity to elevated ... ALP • AST/ALT ... GGT/5-NT: ↑ - ALP ... Tests of synthetic function
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
ALP enzyme- Discovered ... in 1923 Low ALP ... synthesized in: liver ... severe mobility/functional ... intracranial pressure - Elevated
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• In all patients ... Hyperferritinemia - Elevated ... liver enzymes ... Impaired cytotoxic function ... Elevated soluble