13 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Sheet Novel (or Direct ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
Direct-acting oral ... anticoagulants (DOACs ... Table #DOAC ... Anticoagulation #VTE #Management ... #Pharmacology #
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
rivaroxaban are the only direct-acting ... anticoagulants (DOACs ... = direct-acting ... Anticoagulation #Management ... #Hematology #Oncology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
rivaroxaban - Direct ... anticoagulation #pharmacology ... #medications #doac ... #comparison #table ... #management #drugs
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... DOACs are substrates ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... patients taking direct ... • Dabigatran (direct ... Perioperative #Management ... #Treatment #pharmacology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
LMWH, warfarin, DOACs ... (e.g. direct factor ... Xa inhibitors, direct ... Summary #table #comparison ... #diagnosis #hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management ... #Hematology #Oncology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... not available #DOAC ... #Reversal #NOAC ... anticoagulant #hematology ... #management #pharmacology
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
Disease, Mechanical Defect ... vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... inopressors #diagnosis #management ... #comparison #table