1950 results
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
Medical Therapy (GDMT ... pillars of HFrEF GDMT ... disease: ACEI, ARB ... Medications that are ... but are commonly
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
DharSaty #HFrEF #GDMT ... angiotensinreceptorblockers #ARB
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
HFrEF) Treatment - GDMT ... Medical Therapy (GDMT ... GDMT is basically ... them on ACEI or ARB ... tolerated ACEI/ARB
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
Beta-blocker • ACE, ARB ... Guideline #management #GDMT
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
On" • ACEI, ARB ... increasing ACEI or ARB ... Reducing: • ACEI or ARB ... chf #cardiology #GDMT
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
Approach: ACE, ARB ... Guideline #management #GDMT
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
fibrillation; ARB ... ejection fraction; GDMT
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Pregnancy • Avoid ARB ... Avoid ARBs • ICD ... complications are ... pregnancy, teratogenic GDMT ... meds (e.g., ACE/ARB
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
outcomes in HFrEF on GDMT ... outcomes in HFrEF on GDMT
Antenatal Visits - Testing and Schedule
At Every Visit:	
 • Gestational Age	
 • BP
 • Maternal Weight
, Parvovirus GDM ... Stillbirth GDM ... after - GDM ... Additional U/S If there are