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differential vasculitis erythematosus systemic arthropathies arthropathy criteria cryoglobulinemia cryoglobulins dermatology disorders eularacr glomerulonephritis management monoarthritis monoarticular msk pain polyarthritis polyarticular
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... Algorithm Monoarthritis ... with Systemic Lupus ... Erythematosus (SLE ... should have other symptoms
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... ANCA (C-ANCA): GPA ... #differential #diagnosis ... #algorithm #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Sarcoidosis • GPA ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... in at least 2 joints ... #Criteria #SLE ... Erythematosus #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... #SLE #systemic ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Arthritis: • Joint ... : • Symptoms limited ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... • Progressive symptoms ... Palpable purpura, joint ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... and branches • GCA ... vasculitis, and SLE ... #rheumatology # ... classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... (e.g. systemic lupus ... erythematosus (SLE ... #types #classification ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... ear • Skin • Joints ... cases such as: • SLE ... Polychondritis #rheumatology
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