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differential arthritis oncology classification joint management msk sle algorithm erythematosus leukemia systemic vasculitis causes cll comparison disease druginduced hodgkins infections
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Diagnosis Algorithm ... Deficiency • Aplastic ... of Chronic Disease ... Algorithm #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... → Refer to hematology ... for workup, including ... • Infections: Chronic ... #Algorithm #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... lesions Abdominal pain ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... • Evolution: Chronic ... comparison #table #rheumatology ... #diagnosis #management
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... : • Acute or chronic ... #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... Pain - Diagnostic ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... Differential Diagnosis ... constitutional symptoms ... #Differential #Diagnosis ... #MSK #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Arthritis: • Joint pain ... lymphopenia, low PLT • Anemia ... : • Symptoms limited ... : • Chronic B-cell ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... • Neutropenia, anemia ... Pure red cell aplasia ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... , fever, joint pain ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
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