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hematology arthritis oncology erythematosus pain systemic approach disorders monoarthritis monoarticular polyarthritis polyarticular signs vasculitis algorithm arthropathies arthropathy autoantibodies causes chronic
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... Erythematosus (SLE ... should have other symptoms ... #Disorders #msk ... #Differential #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... Diagnosis and Lupus ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... bone pain, fever, joint ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... : • Symptoms limited ... Hodgkin lymphoma and leukemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... phenomenon CLL Diagnosis ... • Neutropenia, anemia ... #diagnosis #workup
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS+GI+CVS+joints ... (-) hemolytic anemia ... to cold IgG • Lupus ... #Monoclonal #Differential ... #Diagnosis #Oncology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... Diagnosis Framework ... constitutional symptoms ... #Diagnosis #MSK ... #rheumatology #
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