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differential hematology management signs erythematosus oncology sle systemic ana antibodies antinuclear associations autoantibodies causes classification comparison diseases algorithm arthritis dermatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... causes: • Susac syndrome ... • Sjögren syndrome ... • Systemic lupus ... ANCA-associated vasculitides
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Churg-Strauss syndrome ... purpura-arthralgia-nephritis syndrome ... - Goodpasture syndrome ... - Schnitzler syndrome ... - Sjögren syndrome
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... Polymerase Ill • ANCA Vasculitis ... #diagnosis #associations ... #table
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Hyperviscosity syndrome ... CVST • Bing-Neel syndrome ... (Dermato-neuro syndrome ... dermatosis) • Gleich syndrome
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... - Budd Chiari Syndrome ... pathophysiology #signs #symptoms ... #diagnosis
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
• Cushing’s syndrome ... Renal: • Acute GN ... Autoimmune: • Vasculitis ... • Lupus • Polyarteritis ... • Serotonin syndrome
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... Instability, Felty's Syndrome ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Mucocutaneous lymph node syndrome ... • Progressive symptoms ... • Behcet syndrome ... • Cogan syndrome ... #Rheumatology
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