9 results
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Vasculitis • GN ... Med, Contrast, Pigment ... #AKI #Acute #Kidney ... nephrology #causes #algorithm
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... FSGS, Membranous GN ... @kdjhaveri #DrugInduced ... differential #diagnosis #algorithm ... #nephrology #Medications
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... • Limited to Kidney ... differential #diagnosis #algorithm ... #rheumatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Differential Diagnosis Algorithm ... Congenital Medications ... Destruction • Systemic ... Lupus Erythematosus ... #Causes #Hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... myalgia, serositis, Kidney ... months to years) Systemic ... Lupusreference #druginduced ... #table #rheumatology
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... associated with systemic ... lupus erythematosus ... Nephritis #diagnosis #algorithm ... nephrology #biopsy #indications
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... C4) • ds-DNA: Kidney ... induced SLE • Kidney ... activation and/or medications
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Lupus Erythematosus ... Lupusreference #DrugInduced ... #medications #drugs ... differential #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... inflammation Others: • Lupus ... lupus erythematosus ... Kidneys -> glomerulonephritis ... differential #diagnosis #rheumatology