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diagnosis differential hematology algorithm lad classification diffuse focal localized vasculitis glomerulonephritis hodgkins leukemia lymphoma management monoclonal paraproteinemias progressive rapidly rpgn
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... and Localized Lymphadenopathy ... Focal #Localized #Lymphadenopathy ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphadenopathy ... • Systemic Lupus ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Lymphadenopathy ... Localized #Focal #Lymphadenopathy ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... diagnosis #algorithm #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Immunotactoid GN ... -C3 GN • Cast ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
pain • Bulky lymphadenopathy ... & BM • Bulky lymphadenopathy ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Presentation: • Lymphadenopathy ... Lymphoma (90-95% of cases ... classification #hematology ... #oncology #management
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