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diagnosis hematology differential algorithm lad leukemia chronic cll diffuse focal localized lymphocytic management classification extravascular hemeonc hemolysis hemolytic hodgkins intravascular
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... and Localized Lymphadenopathy ... Neoplastic (Leukemia, Lymphoma ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphadenopathy ... • Systemic Lupus ... Non-Hodgkin's Lymphoma ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Lymphadenopathy ... •TB • Lymphoma ... Forearm/Hand) • Lymphoma ... #Hematology #Oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... Marginal zone lymphoma ... (-) hemolytic anemia ... to cold IgG • Lupus ... Differential #Diagnosis #Oncology
Great Mimickers - SHALLOTS Mnemonic S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
dermatitis, dementia, anemia ... What doesn't HIV cause ... anything L - Lupus ... Could be lupus in ... yeah all that lymphadenopathy
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Presentation: • Lymphadenopathy ... Weight loss • Anemia ... Immune hemolytic anemia ... classification #hematology ... #oncology #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... , CLL, lymphoma, ... Extravascular #Causes ... #anemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
early symptoms • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... and secondary lymphoid ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... to large cell lymphoma ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
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