10 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
) RPGN has three ... pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... diagnosis #algorithm #rheumatology
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Causes of Diffuse ... and Localized Lymphadenopathy ... Focal #Localized #Lymphadenopathy ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Lymphadenopathy ... • Systemic Lupus ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Causes of Localized ... Lymphadenopathy ... Localized #Focal #Lymphadenopathy ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Immunotactoid GN ... -C3 GN • Cast ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
basement membrane; GN ... atypical HUS; MPGN ... cell/white cell casts ... , infiltrates, lymphadenopathy ... Nephrocalcinosis causes
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
early symptoms • Lymphadenopathy ... Exam/Signs: • Lymphadenopathy ... • MPGN: Paraneoplastic ... diagnosis #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
pain • Bulky lymphadenopathy ... & BM • Bulky lymphadenopathy ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Presentation: • Lymphadenopathy ... Lymphoma (90-95% of cases ... classification #hematology ... #oncology #management