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diagnosis differential hematology algorithm ana anca antibody antineutrophil antinuclear classification diffuse diseases lymphadenopathy management monoclonal paraproteinemias sjogrens syndrome vasculitides
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lupus Erythematosus ... Leukemia - History of Bleeding ... Lymphadenopathy #LAD ... #Hematology #Oncology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... drug-induced SLE) • Systemic ... Anti-La/SSB • ... ANCA-Associated Vasculitis ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Autoantibodies: • WAIHA • CAD ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... tract, and often causes ... lupus erythematosus ... C-ANCA) pattern: antibodies ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... Membranoproliferative GN ... Vasculitis: • ... Sjogrens #Syndrome #Rheumatology
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