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diagnosis management chronic druginduced leukemia lymphocytic cell comparison differential dil gammopathy hemeonc hodgkins lymphoma mds mgrs myelodysplasia myelodysplastic nephritis nephrology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Lymphoma (HCV) • CLL ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... severity (ISN/RPS classification ... by 12 months Classification ... Nephritis #Management #treatment ... #management #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... microglobulin Treatment ... leukemia #CLL ... Leukemia #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... fludarabine) 3) Monoclonal ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... • Immunologic Workup ... • Immunologic Workup ... life-threatening • Treatment ... comparison #table #rheumatology
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Diagnostic Workup ... guide subtype classification ... immunotactoid GN ... cryoglobulinemic GN ... microangiopathy Treatment
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... -95% of cases) Classification ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Epidemiology: -10% of all ... • Immunologic Workup ... constitutional symptoms • Treatment ... #DIL #rheumatology ... #diagnosis #treatment
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
tissue composed of monoclonal ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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