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diagnosis algorithm causes aki ana kidneyinjury nephrology patterns vasculitis arthritis classification dermatology disease erythematosus laboratory management petechiae petechial progressive rapidly
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... Purpura Anti-GBM antibodies ... #Vasculitis #differential ... diagnosis #algorithm #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
, Drug-induced Lupus ... Kumfer @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Kidney Injury AKI - Differential ... INTRINSINC RENAL Glomerulonephritides ... (GN) • Primary ... Post-infectious GN ... , Lupus Acute Tubular
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Injury (AKI) - Differential ... Rapidly Progressive Glomerulonephritis ... • Anti-GBM antibodies ... IgA, post-strep, lupus ... legionella) • Immune (lupus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology ... #diagnosis #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Autoimmune Vasculitis (lupus ... Measurement of antinuclear ... cytoplasmic antibodies ... #dermatology #physicalexam
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... inflammation Others: • Lupus ... such as systemic lupus ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Pleural effusions • Acute ... 1, SCL-70, RNP antibodies
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... antibodies ≥ 1: ... acidosis • NAGMA • Glomerulonephritis ... Membranoproliferative GN ... Sjogrens #Syndrome #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... double-stranded DNA antibodies ... Screening Tests for Acute
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