8 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Complement: Post-strep GN ... , Lupus Nephritis ... Glomerulonephritis #Vasculitis ... #differential #
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... ANCA associated vasculitis ... (RA), Systemic lupus ... erythematosus (SLE ... #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
, proteinuria, rapidly ... progressing GN ... tract, and often causes ... purpura: strong sign ... #rheumatology #
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria - Differential ... hematuria • Signs ... or vasculitis ... Radiation • Rapid ... #Hematuria #Differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... purpura: Strong sign ... tract, and often causes ... Diagnosis #Rheumatology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... (systemic lupus ... infections - Vasculitis ... pediatrics #diagnosis #differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Bleeding and Bruising ... of Hemostasis - Differential ... inhibitor and lupus ... discern these causes ... integrity == • Vasculitis
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
cord resulting in rapid ... • Bilateral signs ... Disorders: - SLE ... - Sjogren - Vasculitis ... management #neurology #differential