9 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
to complement activation ... Type Ill - IgG and ... Complement activation ... systemic lupus ... #Classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... low C4, Low C3 and ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... Type 1 - Mediators ... to complement activation ... glomerulonephritis, Systemic lupus ... allergy #table #classification
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
IgA nephropathy, lupus ... post-infectious GN ... autoAb against type ... ) + • c-ANCA: ... Glomerulonephritis #RPGN #Classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... • Type III Often ... (e.g. systemic lupus ... #classification ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... disease • Systemic lupus ... SJIA], systemic lupus ... Histopathologic criteria ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Non-autoimmune rheumatologic ... Kikuchi disease • Type-I ... Chronic B-cell activation ... Erythematosus #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... such as systemic lupus ... LFT • ESR • ANA ... differential #diagnosis #rheumatology ... #classification
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
including monkeypox virus ... detect monkeypox virus ... 2022-lab-advisory-CLARIFICATION-CDC_Publishes_Non-variola_Orthopoxvirus_PCR_Testing_Procedure ... patient meets the criteria ... The type of specimen