14 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Erythematosus ... Lupusreference #Renal #diseases ... #venn #nephrology ... #nephritis #classification ... #types #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... Non-autoimmune rheumatologic ... • Type-I Interferonopathies ... antibodies • (-) ANA ... #Diagnosis #Rheumatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... Inflammatory and ... : • Systemic lupus ... erythematosus ... • Epstein-Barr virus
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... - systemic lupus ... erythematosus ... dermatomyositis #Size #Classification ... Vessels #Diagnosis #Rheumatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
binds to the lgE, cross-linking ... during hemolytic disease ... systemic lupus ... erythematosus Type ... #Classification
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Cerebrovascular Disease ... #Erythematosus ... #SLE #CNS #neurology ... #rheumatology #
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Chain deposition disease ... S - Systemic Lupus ... Erythematosus ( ... Ann Marie Kumfer ... #differential #hematology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... IgA nephropathy, lupus ... post-infectious GN ... autoAb against type ... Differential #Diagnosis #Nephrology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... (e.g. systemic lupus ... erythematosus ( ... #classification ... #rheumatology #
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... erythematosus Type ... allergy #table #classification