19 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Renal Involvement ... #diseases #SLE ... Erythematosus #venn #nephrology ... #nephritis #classification ... #types #rheumatology
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... #Classification ... #differential #types ... #rheumatology # ... nephrology #renal
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... IgA nephropathy, lupus ... post-infectious GN ... autoAb against type ... Differential #Diagnosis #Nephrology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
binds to the lgE, cross-linking ... during hemolytic disease ... Type Ill - IgG and ... systemic lupus ... #Classification
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Chain deposition disease ... S - Systemic Lupus ... Erythematosus (total 50, renal ... Ann Marie Kumfer ... #differential #hematology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
or 0.5 g/day → renal ... severity (ISN/RPS classification ... by 12 months Classification ... treatment #management #rheumatology ... #nephrology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Classification of ... Histiocytosis and ... Acquired - Primary renal ... Diabetes #Insipidus #Classification ... #Types #Nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... Classification: ... Non-autoimmune rheumatologic ... • Type-I Interferonopathies ... APLA/LAC: • Renal
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... vascular beds-renal ... Paraproteinemias #Hematology
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Lupus Benefits ... : ↓ Disease activity ... needed in case of renal ... #Benefits #Lupus ... #sideeffects #rheumatology