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diagnosis differential erythematosus systemic allergy antinuclear hypersensitivity patterns reactions table vasculitis autoantibodies comparison criteria cryoglobulinemia cryoglobulins disease eularacr laboratory management
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... Juvenile Idiopathic Arthritis ... #Antinuclear #Antibodies ... #rheumatology #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... Juvenile Idiopathic Arthritis ... #Antinuclear #Antibodies ... #rheumatology #diagnosis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... • Arthritis domain ... Highly specific antibodies ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Non-autoimmune rheumatologic ... Kikuchi disease • Type-I ... 1, SCL-70, RNP antibodies
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Auto-Antibodies ... : - ANA 95-100% ... Lupusreference #SLE ... #differential #rheumatology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Allergen-specific lgE antibodies ... Type Ill - IgG and ... glomerulonephritis, rheumatoid arthritis ... , and systemic lupus ... #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthritis) • ... Types II and III ... (e.g. systemic lupus ... #classification ... #rheumatology #
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... Action: IgG/lgM antibodies ... Examples: Rheumatoid arthritis ... glomerulonephritis, Systemic lupus ... allergy #table #classification
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... antibodies, which ... Tests for All Types ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... ) pattern: antibodies ... SLE) • Urinalysis ... differential #diagnosis #rheumatology ... #classification
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