12 results
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Inflammatory Joint Pain ... • Systemic Lupus ... Erythematosus • Sjögren's ... Inflammatory #JointPain #MSK ... #Orthopedics #Causes
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... of hip (rare), Arthritis ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... likely it will be clinically ... Juvenile Idiopathic Arthritis ... erythematosus (SLE), Sjogren's ... ANA #patterns #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
weeks) Can Be Caused ... - Autoimmune Rheumatologic ... • Hepatitis B virus ... #Diagnosis #MSK ... #rheumatology #
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... ) - MSK Radiology ... - **MSK rads ... #mri #clinical ... #msk #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... dermatomyositis, Sjogren ... Non-autoimmune rheumatologic ... lymphoproliferative syndrome Clinical ... : • Joint pain
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... (e.g. systemic lupus ... classification #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... spondyloarthropathies, lupus ... Like in this case ... #Joint #Pain #MSK ... #rheumatology #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Membranoproliferative GN ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... #Syndrome #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology