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diagnosis differential hematology syndrome vasculitis causes disease erythematosus management msk oncology signs sle symptoms systemic workup algorithm approach bone classification
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Pain Rash ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... differential #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Lyme), reactive arthritis ... #Joint #Pain #MSK ... #rheumatology #
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... with temporal arteritis ... Diffuse muscle pain ... uncommon 5-15% of lupus ... diagnosis #comparison #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis ... - Autoimmune Rheumatologic ... • Hepatitis B virus ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... in small joints ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Pain in Sickle ... Osteomyelitis / Septic Arthritis ... BrighamChiefs #Bone #Joint ... diagnosis #causes #hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
• Epstein-Barr Virus ... Destruction • Systemic Lupus ... • Rheumatoid Arthritis ... Algorithm #Causes #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... • Fever is the main ... SJIA], systemic lupus ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... : • Joint pain ... arthropathy • 90% joints ... Chronic B-cell activation ... Erythematosus #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Immunotactoid GN ... -C3 GN • Cast ... Scleromyxedema (CNS+GI+CVS+joints ... to cold IgG • Lupus ... Paraproteinemias #Hematology
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