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diagnosis differential management hematology syndrome vasculitis disease erythematosus msk myopathy myositis oncology rheumatoid sle symptoms systemic workup activation antimda5 antimda5dm
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Pain Rash ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #joint #pain #skin ... differential #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Lyme), reactive arthritis ... #Joint #Pain #MSK ... #rheumatology #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis ... noninflammatory Signs ... - Autoimmune Rheumatologic ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... with temporal arteritis ... and/or joint aches ... • +ANA, +Anti-Smith ... diagnosis #comparison #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... lesions Abdominal pain ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... knees, shoulders Signs ... pain / swelling ... history, exam and ... diagnosis #management #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... XR, MRI to dx and ... Osteomyelitis / Septic Arthritis ... BrighamChiefs #Bone #Joint ... diagnosis #causes #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... tract: Abdominal pain ... Palpable purpura, joint ... and GN Anti-GBM ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... : • Joint pain ... arthropathy • 90% joints ... antibodies • (-) ANA ... Erythematosus #Diagnosis #Rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... nonerosive inflammatory arthritis ... thickening • Osteitis: pain ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
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