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diagnosis differential erythematosus management myopathy rheumatoid sle syndrome systemic vasculitis antimda5dm autoimmune classification comparison dermatomyositis disease monoarthritis monoarticular msk myopathies
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... Rheumatica • Pain ... with temporal arteritis ... and/or joint aches ... diagnosis #comparison #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... lesions Abdominal pain ... Glomerulonephritis Myositis ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... knees, shoulders Signs ... pain / swelling ... effusions, reduced ROM Laboratory ... diagnosis #management #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis ... noninflammatory Signs ... - Autoimmune Rheumatologic ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fever) and laboratory ... Non-autoimmune rheumatologic ... : • Joint pain ... arthropathy • 90% joints ... with: • Minimal laboratory
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
interphalangeal joints ... • Arthralgia/arthritis ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... nonerosive inflammatory arthritis ... other etiology • Laboratory ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... level to exclude myositis ... low back pain) ... #laboratory #workup
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... vesicular eruption • Joints ... Palpable purpura, joint ... and GN Anti-GBM ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... vesicular eruption - Joints ... purpura: strong sign ... LFT • ESR • ANA ... differential #diagnosis #rheumatology
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