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differential hematology algorithm syndrome approach classification diffuse isolated joint leukemia lymphadenopathy management monoclonal msk myocarditis neutropenia paraproteinemias sapho sweet vasculitides
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... • Rheumatoid Arthritis ... Lymphadenopathy #LAD ... #Hematology #Oncology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... • Epstein-Barr Virus ... Destruction • Systemic Lupus ... • Rheumatoid Arthritis ... #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoantibodies: • WAIHA • CAD ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Causes of Myocarditis 1. Infectious Myocarditis • Bacterial - Staphylococcus, Streptococcus, Pneumococcus, Meningococcus, Gonococcus, Salmonella, Corynebacterium
disorders: Systemic lupus ... erythematosus, rheumatoid arthritis ... Copper, iron, lead ... #differential #diagnosis ... #cardiology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... - Diagnostic Framework ... spondyloarthropathies, lupus ... Like in this case ... #rheumatology #
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
malaise) - Muscle pain ... Inflammation and pain ... Causes: - Idiopathic ... ’s syndrome - Lupus ... #dermatology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... tract, and often causes ... such as systemic lupus ... retinopathy Lab ... #rheumatology #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... Rule out other causes ... TNF blockers had ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... activity • ↓ LAP ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
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