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diagnosis management classification differential druginduced erythematosus syndrome systemic activation ana antinuclear comparison disease eularacr laboratory macrophage mas patterns pmr polymyalgia
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Clinical Domains ... • Arthritis domain ... #SLE #Systemic ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... Constitutional symptoms, Arthritis ... , SCLE-DIL (terbinafine ... thiazidic, PPI, ACE ... #table #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... assay (IFA) is the main ... likely it will be clinically ... ANA #patterns #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Non-autoimmune rheumatologic ... : • Joint pain ... Erythematosus #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Fever is the main ... erythematosus [SLE ... Histopathologic criteria ... Diagnosis #Management #Hematology ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... , and low back pain ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
American College of Rheumatology Diagnostic Criteria for Gout Presence of characteristic urate crystals in the joint fluid
American College of Rheumatology ... the following clinical ... - Pain or redness ... #Rheumatology # ... ACR
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 Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... , SCLE-DIL (terbinafine ... thiazidic, PPI, ACE ... #DIL #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... such as systemic lupus ... C-ANCA) pattern: antibodies ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... Membranoproliferative GN ... Arthralgia and Arthritis ... Sjogrens #Syndrome #Rheumatology
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