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diagnosis differential erythematosus management systemic classification criteria druginduced joint msk vasculitis activation ana antibodies antinuclear approach comparison dil disease eularacr
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... • Arthritis domain ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE ... • Immunologic Workup ... #table #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Crystal induced (Gout ... fever • Lyme • Gout ... • SLE • Psoriatic ... Symmetrical: • RA • SLE ... Diagnosis #MSK #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: ... of hip (rare), Arthritis ... lesions Abdominal pain ... symptoms #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... likely it will be clinically ... Juvenile Idiopathic Arthritis ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Non-autoimmune rheumatologic ... : • Joint pain ... Erythematosus #Diagnosis #Rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #rheumatology # ... approach #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... , and low back pain ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Fever is the main ... SJIA], systemic lupus ... erythematosus [SLE ... Diagnosis #Management #Hematology ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... tract: Abdominal pain ... purpura, joint & gut ... involvement, abdominal pain ... Differential #Diagnosis #Rheumatology
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