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diagnosis differential syndrome druginduced erythematosus systemic activation antibodies antinuclear arteritis behcet classification comparison dil disease gca giantcell hematology indications macrophage
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Polyarteritis Nodosa (PAN ... ), ANCA associated ... (RA), Systemic lupus ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Juvenile Idiopathic Arthritis ... ), Sjogren's Syndrome ... , Sjögren Syndrome ... #patterns #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Antinuclear (ANA ... heart block • Sjogren ... severe disease Treatment ... Summary #diagnosis #rheumatology ... #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Workup: - ANA ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... dermatomyositis, Sjogren ... Non-autoimmune rheumatologic ... : • Joint pain ... Erythematosus #Diagnosis #Rheumatology
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
cell arteritis ... except for: • Aortitis ... #Management #Relapses ... #Indications #rheumatology ... #2ndline
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... claudication, aortitis ... LFT • ESR • ANA ... SLE) • Urinalysis ... differential #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Fever is the main ... erythematosus [SLE ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
: SLE, Reactive ... Arthritis, AS Treatment ... Nonsurgical abdominal pain ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Membranoproliferative GN ... Arthritis Malignancy ... #Syndrome #Rheumatology ... #Diagnosis #Management
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