10 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... Sarcoidosis • GPA ... lesions • Discoid lupus ... erythematosus ... differential #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
(GCA), Takayasu's ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus ( ... Differential #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
rapidly progressing GN ... : erythematous nodules ... such as systemic lupus ... erythematosus, ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
develop in pts with GCA ... : Erythematous nodules ... tract: Abdominal pain ... involvement, abdominal pain ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Non-autoimmune rheumatologic ... : • Joint pain ... Seizures • Strokes Skin ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... lesions Abdominal pain ... SLE #systemic #erythematosus
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
burning sensation or pain ... purpuric macules • Erythematous ... • Ulcerated, erythematous ... • Giant cell arteritis ... rash #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... reticularis & skin ... (e.g. systemic lupus ... erythematosus ( ... classification #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
arteritis (GCA) ... claudication: pain ... required due to skip ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Membranoproliferative GN ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management