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diagnosis differential syndrome classification signs symptoms systemic activation aortitis behcet cryoglobulinemia cryoglobulins dermatology disease hematology joint macrophage mas rashes sjogrens
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... Vesicopustule on erythematous ... lesions • Discoid lupus ... erythematosus ... differential #diagnosis #rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... erythematosus ( ... SLE), Sarcoidosis ... Differential #Diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Non-autoimmune rheumatologic ... : • Joint pain ... Seizures • Strokes Skin
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... lesions Abdominal pain ... #erythematosus #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... : erythematous nodules ... erythematosus, ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... : Erythematous nodules ... tract: Abdominal pain ... involvement, abdominal pain ... Differential #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... (e.g. systemic lupus ... erythematosus ( ... SLE), rheumatoid ... classification #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... : SLE, Reactive ... Nonsurgical abdominal pain ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... erythematosus [ ... SLE], AOSD) • Infection ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Membranoproliferative GN ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... #Diagnosis #Management
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