24 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
: Summary Type ... complexes • Ex: Systemic ... Lupus Erythematosus ... , Reactive Arthritis ... #Allergy #Allergic
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... : • Systemic Lupus ... • Erythematosus ... : • Arthritis ... HypersensitivityReaction #Allergy
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... - Local and systemic ... glomerulonephritis, rheumatoid arthritis ... , and systemic lupus ... erythematosus
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Lupus Erythematosus ... • Rheumatoid Arthritis ... • Acne • Allergy ... #Hematology #Oncology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
of hypersensitivity ... lgE causes mast-cell ... Examples: Rheumatoid arthritis ... glomerulonephritis, Systemic ... lupus erythematosus
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
• Epstein-Barr Virus ... Destruction • Systemic ... Lupus Erythematosus ... • Rheumatoid Arthritis ... #Hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
GCA), Takayasu's arteritis ... (RA), Systemic ... lupus erythematosus ... (SPA) • Other Causes ... Differential #Diagnosis #rheumatology
Causes of Myocarditis
Infectious Etiologies:
 • Viral agents: Adenoviruses, Enteroviruses (coxsackievirus), Herpesviruses (human herpesvirus 6, Epstein—Barr virus),
Causes of Myocarditis ... Interleukin-2 • Hypersensitivity ... , Sarcoidosis, Systemic ... lupus erythematosus ... , Takayasu arteritis
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
central nervous system ... vasculitis - hypersensitivity ... disease - systemic ... lupus erythematosus ... Vessels #Diagnosis #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... vasculitis • Hypersensitivity ... lupus erythematosus ... classification #rheumatology